Best Prostate Cancer Clinics in Milan: Where to Go and How to Get an Appointment

by Dr. Jonas Witt
Medical Doctor
August 14, 2026
9 min
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Table of Contents

TL;DR

  • Milan has several specialist centres for prostate cancer, including IEO, Istituto Nazionale dei Tumori, San Raffaele, Policlinico di Milano, and Humanitas.
  • There is no single clinic that is automatically best for everyone. The right choice depends on your diagnosis, stage, treatment needs, access route, and personal priorities.
  • SSN appointments generally require an impegnativa, while private consultations can usually be booked directly with the hospital.
  • Preparing PSA results, biopsy reports, MRI or PET imaging, medication lists, and written questions can make a specialist visit easier to follow.
  • Experiences shared through the mama health app often highlight uncertainty around PSA, Gleason score, treatment options, side effects, and what to ask during appointments.

Choosing where to go for prostate cancer care can feel difficult, especially when several highly specialised hospitals are available in the same city. Milan is home to major cancer institutes, university hospitals, and urology centres with access to multidisciplinary care.

The centres below are not ranked from best to worst. Each has different strengths, and the most suitable option depends on your medical situation and what you need from the appointment.

Which prostate cancer clinics in Milan should you consider?

Several Milan centres provide specialist prostate cancer care across diagnosis, surgery, radiotherapy, medical oncology, imaging, and follow-up.

Among the main options are Istituto Europeo di Oncologia, Istituto Nazionale dei Tumori di Milano, IRCCS Ospedale San Raffaele, Policlinico di Milano, and Humanitas Research Hospital in Rozzano.

The most relevant centre may differ depending on whether you are looking for a first specialist opinion, surgery, radiotherapy, assessment of advanced disease, a second opinion, or information about clinical trials.

Why might you consider the Istituto Europeo di Oncologia?

The Istituto Europeo di Oncologia is one of Milan's major specialist cancer centres and has dedicated expertise in prostate disease and urological oncology.

IEO's Division of Urology manages prostate and other urological cancers using surgical, endoscopic, and robotic approaches. The institute also describes a multidisciplinary programme focused on prostate disease.

This may be useful when more than one specialist needs to review the same case, such as a urologist, radiation oncologist, medical oncologist, radiologist, or pathologist.

How do you book an appointment at IEO?

IEO accepts appointments through its CUP and online booking systems.

For SSN appointments, availability can also be searched through the Regione Lombardia booking system. IEO lists its CUP for visits and examinations as +39 02 57489 001.

Private and insurance-covered consultations are also available.

When booking, it can help to explain whether you are looking for a first urology consultation, review after an abnormal PSA result, an opinion following biopsy, or a prostate cancer second opinion.

Why might you consider the Istituto Nazionale dei Tumori di Milano?

The Istituto Nazionale dei Tumori has a dedicated Prostate Cancer Unit built around multidisciplinary prostate cancer care.

Its services include urological oncology, genitourinary medical oncology, radiotherapy, imaging, pathology, and other cancer specialties within the same institute.

This structure may be particularly relevant when a case needs input from several disciplines rather than a consultation focused on one treatment option.

How do you book an appointment at the Istituto Nazionale dei Tumori?

The institute provides booking through its Centro Unico di Prenotazione, or CUP.

The central booking number listed by the institute is +39 02 2390 1.

For an SSN first visit, you will generally need an appropriate medical referral. Private consultations can be booked through the institute's private-care service.

If you already have biopsy slides, pathology reports, MRI scans, PET/CT images, or records from another hospital, ask when booking whether they should be uploaded or brought to the appointment.

Why might you consider Ospedale San Raffaele?

San Raffaele is a major Milan urology centre with extensive experience in prostate cancer surgery and research.

Its Urology Unit reports having performed more than 10,000 radical procedures for prostate cancer. The hospital also works in prostate imaging, biopsy techniques, minimally invasive procedures, and research.

San Raffaele may therefore be relevant when discussing surgical approaches or when seeking specialist evaluation of imaging and biopsy findings.

How do you book an appointment at San Raffaele?

For SSN visits and examinations, San Raffaele lists several routes, including the Regione Lombardia booking service and its hospital call centre.

The hospital's SSN booking number is 02 2643 2643.

Private specialist urology appointments can also be booked through the hospital website or booking service.

If you already know which service you need, state this when booking. If not, asking for an initial prostate cancer or uro-oncology consultation can make the request clearer.

Why might you consider Policlinico di Milano?

Policlinico di Milano provides specialist urology services including fusion biopsy and robotic prostate surgery.

The hospital's prostate services include diagnostic assessment and minimally invasive surgical approaches. Its urology service also has experience with robotic surgery for urological cancers.

Fusion biopsy combines MRI information with ultrasound guidance to help specialists sample suspicious prostate areas more precisely in selected situations.

Whether it is appropriate depends on previous PSA results, imaging, examination findings, and specialist assessment.

How do you book an appointment at Policlinico di Milano?

SSN appointments can be booked through the Regione Lombardia system.

Current booking numbers listed by Policlinico are 800 638 638 from a landline and 02 99 95 99 from a mobile phone.

For private consultations through the hospital's libera professione service, the listed booking number is 02 5503 4422.

Why might you consider Humanitas Research Hospital?

Humanitas Research Hospital offers specialist prostate cancer services through its urology and cancer programmes, including robotic surgery and selected focal approaches.

Humanitas is in Rozzano, just outside Milan, but it is commonly considered among the major specialist hospitals in the Milan metropolitan area.

Its Urology Unit has experience in laparoscopic and robotic surgery for urological cancers. Humanitas has also worked on prostate imaging, PSMA PET/CT research, high-resolution ultrasound, and focal treatment approaches.

Focal treatment is not suitable for every prostate cancer. Whether it is worth discussing depends on tumour location, grade, stage, imaging findings, and other individual factors.

How do you book an appointment at Humanitas?

For SSN information and appointments, Humanitas currently lists 02 8224 8282.

For private and insurance-covered appointments, the listed number is 02 8224 8224.

For an SSN visit, Humanitas states that an impegnativa medica is required.

Which Milan prostate cancer clinic is best for your situation?

The best centre is usually the one that provides the expertise your specific situation requires.

Someone with an elevated PSA who has not yet had an MRI may need different expertise from someone with biopsy-confirmed prostate cancer deciding between surgery and radiotherapy.

Someone seeking another opinion after recurrence may need access to medical oncology, nuclear medicine, PSMA imaging, radiotherapy, or clinical trials.

When comparing centres, useful questions include whether the hospital has a dedicated prostate or uro-oncology service, whether cases are discussed across specialties, whether surgery and radiotherapy are both available, whether prostate MRI and targeted biopsy are offered, and whether advanced-disease services and clinical trials are available.

It can also help to ask how urinary, bowel, sexual, and hormonal side effects are discussed before treatment.

What should you prepare before a prostate cancer appointment?

Organising your medical information before the visit can make the discussion easier to follow.

Useful documents may include recent and previous PSA results, prostate MRI reports and images, biopsy reports, Gleason score and Grade Group information, CT or PSMA PET/CT reports, details of previous treatments, a current medication list, relevant medical conditions, and family history.

It can also help to write down questions before the appointment.

If you are unsure what your biopsy report means, the mama health guide to the Gleason score and Grade Groups explains the terminology in simpler language.

For broader context, see what prostate cancer is and how it is assessed.

What do experiences shared through the mama health app show about preparing for specialist visits?

Experiences shared through the mama health app show that many questions appear before and after specialist appointments, not only during them.

Common themes include uncertainty about what a PSA result means, how Gleason score differs from stage, why different specialists may discuss different options, and how possible side effects could affect everyday life.

Experiences also show how easy it can be to leave an appointment with new questions. Medical terminology, test results, and several possible treatment approaches may be discussed within a short period.

This is where preparation can be useful. mama health can provide educational information, help organise questions for personal reference, and make unfamiliar terms easier to understand before a conversation with a healthcare professional.

Questions that may be useful to prepare include:

  • What does my Grade Group mean in my situation?
  • What stage has been identified?
  • Is additional imaging needed?
  • What options could be discussed?
  • Is active surveillance relevant?
  • What urinary, bowel, sexual, or hormonal effects could occur?
  • Would input from another specialty be useful?
  • Is genetic or genomic testing relevant?
  • Are there clinical trials that could be discussed?

These questions do not determine which treatment is appropriate. They can help structure a conversation with the specialist.

You can also read mama health's explanation of prostate cancer stages before your visit.

Is it worth getting a second opinion in Milan?

A second specialist opinion can be useful when more than one reasonable approach is available or when you want another explanation of your results.

Prostate cancer may involve several possible strategies, including active surveillance, surgery, different forms of radiotherapy, hormone-based treatment, or combinations of approaches.

A second opinion does not mean the first recommendation was wrong. It may help clarify why an option was suggested and whether another specialist interprets the available information differently.

If you request another opinion, bring your original pathology report and ask whether the centre also wants biopsy material or imaging for review.

For more context, see what stages I-IV of prostate cancer mean.

Should you choose an SSN or private prostate cancer appointment?

Both routes can provide access to specialist care, but booking procedures, availability, and costs differ.

With the SSN, you will generally need an impegnativa and the appropriate prescription code or priority classification.

Private consultations generally allow direct booking without an SSN referral for the specialist visit, although prescriptions may still be required for certain investigations.

If appointment timing matters, it can be useful to check availability through both routes before deciding.

What should you do if you are travelling to Milan from another region or country?

Contact the clinic before travelling and ask exactly which records should be sent in advance.

Digital copies of MRI, PET/CT, pathology reports, and other imaging may be important. A written medical summary can also help specialists understand previous tests and treatments.

If your documents are not in Italian or English, ask whether translation is required.

For international travel, it can also help to confirm whether the clinic has an international office, what payment arrangements apply, and whether records can be reviewed before the in-person appointment.

How can mama health help before and after a prostate cancer appointment?

mama health provides educational support that can help you organise questions, understand medical terminology, and reflect on what you want to discuss with a healthcare professional.

It does not decide which clinic you should attend and does not determine which treatment is right for you.

Experiences shared in the app can also provide useful context around questions that others have faced, including uncertainty about test results, decisions between different treatment approaches, side effects, and follow-up.

This can be especially useful between appointments, when a new question appears or when a medical report contains unfamiliar terminology.

Explore the mama health prostate cancer hub for educational information covering PSA, stage, Grade Group, treatment approaches, and living with prostate cancer.

You may also find these guides useful:

What is the main takeaway when choosing a prostate cancer clinic in Milan?

Milan offers several highly specialised centres, but the right choice depends on the expertise and services needed for your situation.

IEO, Istituto Nazionale dei Tumori, San Raffaele, Policlinico di Milano, and Humanitas all provide substantial prostate cancer expertise.

Rather than choosing only by reputation, compare the services available, the specialists relevant to your situation, access to imaging and treatment options, appointment routes, and how clearly the centre addresses the questions that matter to you.

Preparing your reports and writing down your priorities before the consultation can make the appointment easier to use effectively.

Disclaimer: This content is informational. mama health offers information and support and does not replace a doctor.

Get Personalized Health Support in 2 Minutes
Answer 9 quick questions to build an AI assistant tailored to your condition, backed by trusted medical knowledge and real experiences from people like you.
+40.000 People
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Sources
  1. Istituto Europeo di Oncologia — Division of Urology, prostate programme and appointment information.
  2. Istituto Nazionale dei Tumori di Milano — Prostate Cancer Unit, Urological Oncology and booking information.
  3. IRCCS Ospedale San Raffaele — Urology, prostate cancer programme and booking information.
  4. Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico — Urology, prostate services and booking information.
  5. Humanitas Research Hospital — Urology, prostate cancer services and contact information.

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