Top 7 Chronic Spontaneous Urticaria Clinics in Milan: Where to Go and How to Get an Appointment

by Dr. Jonas Witt
Medical Doctor
August 21, 2026
9 min
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Table of Contents

TL;DR

  • Milan has several dermatology, allergology, and clinical immunology services with documented experience in chronic urticaria.
  • Policlinico di Milano is particularly notable because it belongs to the international UCARE network for urticaria.
  • The seven options below are not ranked from best to worst. Each offers a different specialist setting and appointment route.
  • For SSN appointments, a medical referral is often required. Several hospitals also offer private booking.
  • Before a visit, it can help to organize photos, symptom dates, medicines, previous reports, and questions. mama health can help you keep this information together and turn it into a structured report for your doctor's appointment.

What is chronic spontaneous urticaria?

Chronic spontaneous urticaria (CSU) is a form of chronic urticaria in which wheals, angioedema, or both recur for more than six weeks without a definite external trigger.

The wheals are typically itchy, raised areas of skin that can appear and disappear within hours. Angioedema causes deeper swelling, often around areas such as the lips or eyelids.

“Spontaneous” is an important part of the name. CSU does not mean that a specific food, cosmetic, detergent, or environmental allergen is necessarily responsible. International guidance distinguishes CSU from chronic inducible urticaria, in which symptoms are linked to defined stimuli such as cold, heat, pressure, or friction.

If you are still getting familiar with the condition, mama health's guide to understanding chronic spontaneous urticaria explains the condition in more detail.

Which chronic spontaneous urticaria clinics can you consider in Milan?

Milan offers several hospital services with documented expertise in urticaria through dermatology, allergology, or clinical immunology.

The clinics below are not presented as a medical ranking. Inclusion is based on publicly available information showing experience with chronic urticaria, CSU, angioedema, or a closely related specialist service. Always confirm current services and booking requirements directly with the hospital.

Policlinico di Milano

Policlinico di Milano is one of the clearest urticaria-focused options in Milan because it is part of the international GA²LEN UCARE network.

The hospital's dermatology team has specific expertise in chronic urticaria, while its allergology service explicitly lists chronic spontaneous urticaria among the conditions it manages. The hospital also publishes specialist information and research related to CSU.

UCARE stands for Urticaria Centers of Reference and Excellence. These centers participate in an international network focused on standards for urticaria care, education, and research.

Address: Via Francesco Sforza 28, 20122 Milan. Some relevant dermatology and allergology services are located in nearby hospital buildings around Via Pace.

How to get an appointment: For first allergology visits through the Italian National Health Service, the hospital lists the Regione Lombardia booking numbers 800 638 638 from a landline and 02 99 95 99 from a mobile phone. Follow-up allergology appointments can use the hospital's dedicated route when indicated on the referral or previous report.

When booking, explain that the reason for the appointment is chronic or recurring urticaria so the booking service can identify the appropriate clinic.

IRCCS Ospedale San Raffaele

IRCCS Ospedale San Raffaele has allergology expertise that specifically includes chronic spontaneous urticaria and angioedema.

Official specialist profiles at San Raffaele describe clinical work involving CSU, angioedema, allergy, immune-related conditions, and biologic therapies. This makes the hospital relevant when looking for an allergology-based assessment within a large research and university hospital.

It is important to distinguish between a hospital with CSU expertise and a dedicated urticaria center. San Raffaele's public information confirms relevant specialist expertise, but it does not present the service in the same way as Policlinico's UCARE designation.

Address: Via Olgettina 60, 20132 Milan.

How to get an appointment: San Raffaele lists 02 2643 2643 as its central booking number for SSN, private, and affiliated appointments across multiple specialist services.

When contacting the booking team, ask which allergology appointment is appropriate for recurring urticaria lasting more than six weeks.

ASST Grande Ospedale Metropolitano Niguarda

Niguarda has a dedicated Allergology and Immunology service and explicitly identifies urticaria and angioedema among the conditions connected with that service.

This makes Niguarda another relevant public-hospital option in Milan. The combination of allergology and immunology can be useful when a doctor considers specialist assessment appropriate for recurring hives, swelling, or a more complex medical history.

Address: Piazza Ospedale Maggiore 3, 20162 Milan.

How to get an appointment: SSN visits can be booked through Regione Lombardia at 800 638 638 from a landline or 02 99 95 99 from a mobile phone.

A referral is generally required for an SSN specialist appointment. Check the wording on the referral and the current booking requirements before scheduling.

Ospedale Luigi Sacco

Ospedale Luigi Sacco has an Allergology and Clinical Immunology service that explicitly lists chronic spontaneous urticaria among its main clinical areas.

The service also covers angioedema and other allergic and immune-related conditions. Its official information describes assessment and follow-up of acute and chronic forms of urticaria, including access to specialist therapies when clinically indicated.

Address: Via G.B. Grassi 74, 20157 Milan.

How to get an appointment: SSN visits can be booked through Regione Lombardia by calling 800 638 638 from a landline or 02 99 95 99 from a mobile phone. Online and pharmacy booking routes are also available in Lombardy.

An appropriate medical referral and health card are normally required for the SSN route.

Ospedale San Paolo

Ospedale San Paolo offers medical allergology services that include urticaria among the conditions seen by the clinic.

The wider ASST Santi Paolo e Carlo allergology service also explicitly refers to acute and chronic urticaria.

This can be a practical option if you are looking for an allergology service in the south-western part of Milan.

Address: Via Antonio di Rudinì 8, 20142 Milan.

How to get an appointment: The hospital supports SSN and private booking. SSN appointments can be requested through Regione Lombardia's booking service. The Medical Allergology clinic also lists 02 8184 4016 and 02 8184 4776 as contact numbers.

When booking, specify that you are looking for an appointment concerning persistent or recurring urticaria rather than a general allergy test.

Auxologico San Luca

Auxologico San Luca provides immunology and allergology services that include urticaria and angioedema.

Auxologico lists both conditions within its Immunology, Allergology and Rheumatology service. Specialist profiles also describe experience in urticaria and angioedema.

The service can be accessed through several payment routes, including the SSN and private options.

Address: Piazzale Brescia 20, 20149 Milan.

How to get an appointment: Auxologico lists 02 61911 2501 for SSN and Smart appointments and 02 61911 2500 for Plus/private and affiliated appointments in Lombardy. Online booking is also available.

For SSN appointments, the booking form asks for information from the medical referral.

IRCCS Ospedale Galeazzi-Sant'Ambrogio

Galeazzi-Sant'Ambrogio is a dermatology-focused option that explicitly lists chronic and physical urticaria among the conditions covered by its dermatology service.

The dermatology unit also works across inflammatory skin conditions, immunodermatology, and allergological dermatology.

Unlike several options above, this route is centered on dermatology rather than a dedicated allergology and immunology service. That may be relevant when skin symptoms are the main reason for seeking specialist input.

Address: Via Cristina Belgioioso 173, 20157 Milan.

How to get an appointment: The hospital lists 02 8737 0500 for SSN outpatient bookings and 02 8737 0505 for private outpatient appointments.

Ask for a dermatology appointment and mention recurring or chronic urticaria when speaking with the booking service.

For options elsewhere in the country, see mama health's guide to urticaria centers across Italy.

Which Milan CSU clinic is the best fit for you?

The most useful way to compare these services is by their documented urticaria expertise, specialty, access route, and location rather than treating the list as a ranking.

Policlinico di Milano stands out for its UCARE designation and dedicated work in chronic urticaria. Ospedale Luigi Sacco also explicitly names CSU within its Allergology and Clinical Immunology service.

San Raffaele has specialist expertise specifically covering CSU and angioedema. Niguarda provides an established Allergology and Immunology route for urticaria and angioedema.

San Paolo offers another public allergology option within Milan. Auxologico combines allergology and immunology within a service accessible through several booking routes. Galeazzi-Sant'Ambrogio provides a dermatology-centered option and explicitly includes chronic urticaria.

The appropriate service depends on your circumstances and the type of referral you have. A doctor can help you discuss which specialty may be appropriate.

Should you see an allergologist or dermatologist for chronic spontaneous urticaria?

Both allergologists and dermatologists can be involved in chronic urticaria care, depending on the service and the individual situation.

CSU involves the skin, but it is not necessarily caused by an external allergen. This is one reason a general allergy test does not automatically identify what is behind recurring chronic hives.

Some Milan hospitals approach CSU primarily through allergology and clinical immunology. Others have specific urticaria expertise within dermatology. The service's documented experience with chronic urticaria can therefore matter more than the specialty name alone.

When contacting a clinic, a useful question is:

“Does this service regularly see chronic spontaneous urticaria or recurring urticaria lasting more than six weeks?”

You can then ask which appointment type the hospital recommends.

For more background on why chronic urticaria can occur without an obvious allergen, read mama health's guide to causes and spontaneous urticaria outbreaks.

What should you ask when booking a CSU appointment?

Ask whether the service sees chronic spontaneous urticaria, which specialty to book, and what documentation is required.

Useful questions include:

  • Does this clinic regularly see chronic spontaneous urticaria?
  • Should I book allergology, clinical immunology, or dermatology?
  • Do I need a medical referral?
  • Does the referral need specific wording?
  • Is the appointment available through the SSN, privately, or both?
  • Should I bring photographs of previous hives or swelling?
  • Should I bring previous blood tests, allergy tests, specialist letters, or medication records?
  • Is there a separate pathway if angioedema is also present?

Confirm these details directly with the hospital because services, booking procedures, and availability can change.

What should you bring to a chronic urticaria appointment?

Bring information that helps you explain what has happened over time, especially if your skin looks normal on the day of the visit.

Wheals can disappear quickly. Photographs taken when they are visible may therefore help you describe what you experienced to a healthcare professional.

You may also find it useful to bring:

  • a timeline of when the symptoms started;
  • photographs of wheals or swelling;
  • a list of current and previous medicines;
  • notes on how often symptoms appear;
  • previous medical reports and test results;
  • details of any patterns you have noticed;
  • notes on sleep, work, exercise, or other daily activities affected by symptoms;
  • questions you want to remember during the appointment.

A pattern you notice does not prove that something is causing CSU. For example, symptoms appearing around stress, heat, exercise, food, or another event do not by themselves establish a medical trigger.

If you want to learn more about treatment approaches before discussing them with a doctor, mama health has a separate guide to antihistamines and longer-term CSU treatment options.

How can experiences from others help you prepare for a CSU appointment?

First-hand experiences can add practical context to medical information, especially when you are trying to work out what to record or what to ask during a short appointment.

Medical guidelines explain how CSU is defined and assessed. Lived experience can answer a different type of question: How do other people organize everything that happens between appointments? What do they remember to photograph? What questions have others found useful to bring up?

mama health combines trusted medical sources with the experience of thousands like you. That means you can explore how others describe day-to-day issues around the same condition while keeping those experiences separate from medical evidence.

Someone else's experience cannot tell you what is causing your symptoms or what medical care is right for you. It can, however, give you another source of context when deciding what you want to record, research, or discuss with your doctor.

How can mama health help you prepare for a specialist visit?

mama health is a free app for everything your condition asks of you, grounded in medical science and the experience of others, so you don't have to figure it out alone.

Ask anything. Answers are shaped by trusted sources, your history, and the experience of thousands like you.

You can use mama health to:

  • ask questions about chronic spontaneous urticaria in plain language;
  • find specialists and care near you, wherever you are;
  • track symptoms and daily experiences for your own reflection;
  • keep notes about possible patterns, medicines, appointments, and questions together;
  • make labs, prescriptions, and reports easier to understand by reading them alongside the history you have shared;
  • see experiences from others living with the same condition;
  • turn the information you record into a structured report you can take to your doctor's appointment.

mama health provides educational information and organization tools. It does not determine whether you have CSU, decide which clinic you need, or make treatment decisions.

When should hives or swelling be treated as urgent?

Breathing difficulty or swelling involving the tongue or throat can require urgent medical attention.

Chronic urticaria itself is different from anaphylaxis, but new breathing difficulty, faintness, or rapidly developing swelling affecting the airway should not be managed as a routine outpatient booking question.

If you are unsure whether symptoms are an emergency, seek appropriate urgent medical advice rather than waiting for a scheduled specialist appointment.

What should you remember before choosing a CSU clinic in Milan?

Look for documented chronic urticaria expertise and confirm the exact appointment pathway before you book.

Policlinico di Milano has the strongest urticaria-specific designation among the options in this guide because of its UCARE status. Other Milan hospitals also have clearly documented expertise in CSU, chronic urticaria, angioedema, or related allergology and dermatology care.

Before the appointment, gathering photos, dates, medicine information, previous reports, and your own questions can make it easier to explain a condition that changes over time.

This content is informational and not medical advice.

Disclaimer: This content is informational and not medical advice. mama health offers information and support and does not replace a doctor.

Get Personalized Health Support in 2 Minutes
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Sources

  1. International EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for urticaria definition, classification, assessment, and management.
  2. Policlinico di Milano — current chronic urticaria, UCARE, allergology, and booking information.
  3. IRCCS Ospedale San Raffaele — specialist information on chronic spontaneous urticaria and hospital booking information.
  4. ASST Grande Ospedale Metropolitano Niguarda — urticaria and angioedema service information and regional booking route.
  5. ASST Fatebenefratelli Sacco — Allergology and Clinical Immunology service and SSN booking information.
  6. ASST Santi Paolo e Carlo — Medical Allergology service at Ospedale San Paolo.
  7. Auxologico — Immunology, Allergology and Rheumatology service and current booking information.
  8. IRCCS Ospedale Galeazzi-Sant'Ambrogio — Dermatology service covering chronic urticaria and current appointment routes.